About MDNL

Menière’s disease (MD) is an inflammatory disorder of the inner ear defined by episodes of vertigo associated with sensorineural hearing loss, tinnitus, and aural fullness. Epidemiological, clinical and molecular research support several mechanisms, including rare genetic variants, leading to autosomal dominant or recessive inheritance, and changes in the immune response.

The MD Atlas of Genes and Cells is an open repository of genomic, epigenomic and transcriptomic datasets hosted by the Kolling Insittute at University of Sydney to facilitate the molecular diagnosis of Meniere disease. These datasets have been generated by a large international collaborative Consortium to define rare genetic variation and immune profiles and support the clinical and molecular diagnosis.